Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy

The type II AAA+ protein p97 is involved in numerous cellular activities, including endoplasmic reticulum-associated degradation, transcription activation, membrane fusion and cell-cycle control. These activities are at least in part regulated by the ubiquitin system, in which p97 is thought to targ...

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Main Authors: Yeung, Heidi O., Förster, Andreas, Bebeacua, Cecilia, Niwa, Hajime, Ewens, Caroline, McKeown, Ciarán, Zhang, Xiaodong, Freemont, Paul S.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971404/
https://ncbi.nlm.nih.gov/pubmed/24598262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130142
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