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Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis

Although the Myc transcription factor has been shown necessary for the oncogenic function of Ras, the contribution of Ras pathway signaling to the oncogenic function of Myc remains unresolved. We report the novel findings that Myc alone induced Ras/Mapk pathway signaling, and increased signaling fol...

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Detalhes bibliográficos
Main Authors: Gramling, M W, Eischen, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374085/
https://ncbi.nlm.nih.gov/pubmed/22301919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.1
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