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Highly Enantioselective Direct Alkylation of Arylacetic Acids with Chiral Lithium Amides as Traceless Auxiliaries

A direct, highly enantioselective alkylation of arylacetic acids via enediolates using a readily available chiral lithium amide as a stereodirecting reagent has been developed. This approach circumvents the traditional attachment and removal of chiral auxiliaries used currently for this type of tran...

詳細記述

保存先:
書誌詳細
主要な著者: Stivala, Craig E., Zakarian, Armen
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373785/
https://ncbi.nlm.nih.gov/pubmed/21744818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja205107x
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