Clustering by Plasma Lipoprotein Profile Reveals Two Distinct Subgroups with Positive Lipid Response to Fenofibrate Therapy

Fibrates lower triglycerides and raise HDL cholesterol in dyslipidemic patients, but show heterogeneous treatment response. We used k-means clustering to identify three representative NMR lipoprotein profiles for 775 subjects from the GOLDN population, and study the response to fenofibrate in corres...

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Detaylı Bibliyografya
Asıl Yazarlar: van Bochove, Kees, van Schalkwijk, Daniël B., Parnell, Laurence D., Lai, Chao-Qiang, Ordovás, José M., de Graaf, Albert A., van Ommen, Ben, Arnett, Donna K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373573/
https://ncbi.nlm.nih.gov/pubmed/22719863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038072
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