Clustering by Plasma Lipoprotein Profile Reveals Two Distinct Subgroups with Positive Lipid Response to Fenofibrate Therapy

Fibrates lower triglycerides and raise HDL cholesterol in dyslipidemic patients, but show heterogeneous treatment response. We used k-means clustering to identify three representative NMR lipoprotein profiles for 775 subjects from the GOLDN population, and study the response to fenofibrate in corres...

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Bibliografski detalji
Glavni autori: van Bochove, Kees, van Schalkwijk, Daniël B., Parnell, Laurence D., Lai, Chao-Qiang, Ordovás, José M., de Graaf, Albert A., van Ommen, Ben, Arnett, Donna K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373573/
https://ncbi.nlm.nih.gov/pubmed/22719863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038072
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