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The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors

The pK(a) values of internal ionizable groups are usually very different than the normal pK(a) values of ionizable groups in water. To examine the molecular determinants of pK(a) values of internal groups, we compared the properties of Lys, Asp and Glu at internal position 38 in staphylococcal nucle...

詳細記述

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書誌詳細
主要な著者: Harms, Michael J., Castañeda, Carlos A., Schlessman, Jamie L., Sue, Gloria R., Bertrand García-Moreno, E
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373015/
https://ncbi.nlm.nih.gov/pubmed/19324049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.039
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