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Arginine: Its pK(a) value revisited
Using complementary approaches of potentiometry and NMR spectroscopy, we have determined that the equilibrium acid dissociation constant (pK(a) value) of the arginine guanidinium group is 13.8 ± 0.1. This is substantially higher than that of ∼12 often used in structure-based electrostatics calculati...
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| Udgivet i: | Protein Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4420524/ https://ncbi.nlm.nih.gov/pubmed/25808204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2647 |
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