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The pK(a) values of acidic and basic residues buried at the same internal location in a protein are governed by different factors
The pK(a) values of internal ionizable groups are usually very different than the normal pK(a) values of ionizable groups in water. To examine the molecular determinants of pK(a) values of internal groups, we compared the properties of Lys, Asp and Glu at internal position 38 in staphylococcal nucle...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373015/ https://ncbi.nlm.nih.gov/pubmed/19324049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.039 |
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