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Pirh2 RING-finger E3 ubiquitin ligase: its role in tumorigenesis and cancer therapy

The ubiquitin-dependent proteasome system plays a critical role in many cellular processes and pathogenesis of various human diseases, including cancer. Although there are a large number of E3 ubiquitin ligases, the majority are RING-finger type E3s. Pirh2, a target of p53 transcription factor, cont...

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Autori principali: Jung, Yong-Sam, Qian, Yingjuan, Chen, Xinbin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372855/
https://ncbi.nlm.nih.gov/pubmed/22673504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.052
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