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Pirh2 RING-finger E3 ubiquitin ligase: its role in tumorigenesis and cancer therapy
The ubiquitin-dependent proteasome system plays a critical role in many cellular processes and pathogenesis of various human diseases, including cancer. Although there are a large number of E3 ubiquitin ligases, the majority are RING-finger type E3s. Pirh2, a target of p53 transcription factor, cont...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372855/ https://ncbi.nlm.nih.gov/pubmed/22673504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.052 |
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