A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge

It has been suggested that poor immunogenicity may explain the lack of vaccine efficacy in preventing or controlling HIV infection in the Step trial. To investigate this issue we vaccinated eight Indian rhesus macaques with a trivalent replication-incompetent adenovirus serotype 5 vaccine expressing...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Reynolds, Matthew R., Weiler, Andrea M., Piaskowski, Shari M., Piatak, Michael, Robertson, Henry T., Allison, David B., Bett, Andrew J., Casimiro, Danilo R., Shiver, John W., Wilson, Nancy A., Lifson, Jeffrey D., Koff, Wayne C., Watkins, David I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372643/
https://ncbi.nlm.nih.gov/pubmed/22569124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.04.082
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller