Dda helicase tightly couples translocation on single-stranded DNA to unwinding of duplex DNA: Dda is an optimally active helicase

Helicases utilize the energy of ATP hydrolysis to unwind double-stranded DNA while translocating on the DNA. Mechanisms for melting the duplex have been characterized as active or passive, depending on whether the enzyme actively separates the base pairs or simply sequesters single-stranded DNA that...

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Bibliografiske detaljer
Main Authors: Byrd, Alicia K., Matlock, Dennis L., Bagchi, Debjani, Aarattuthodiyil, Suja, Harrison, David, Croquette, Vincent, Raney, Kevin D.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372602/
https://ncbi.nlm.nih.gov/pubmed/22504228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.04.007
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