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The Kinetic Mechanism for DNA Unwinding by Multiple Molecules of Dda Helicase Aligned on DNA

Helicases catalyze the separation of double-stranded nucleic acids to form single-stranded intermediates. Using transient state kinetic methods we have determined the kinetic properties of DNA unwinding under conditions that favor a monomeric form of the Dda helicase as well as conditions that allow...

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Detalhes bibliográficos
Main Authors: Eoff, Robert L., Raney, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876234/
https://ncbi.nlm.nih.gov/pubmed/20408588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100061v
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