Φορτώνει......
Design, synthesis and antiviral activity of entry inhibitors that target the CD4-binding site of HIV-1
The CD4 binding site on HIV-1 gp120 has been validated as a drug target to prevent HIV-1 entry to cells. Previously, we identified two small molecule inhibitors consisting of a 2,2,6,6-tetramethylpiperidine ring linked by an oxalamide to a p-halide-substituted phenyl group, which target this site, s...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2012
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372086/ https://ncbi.nlm.nih.gov/pubmed/22524483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3002247 |
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