NOrMAL: accurate nucleosome positioning using a modified Gaussian mixture model

Motivation: Nucleosomes are the basic elements of chromatin structure. They control the packaging of DNA and play a critical role in gene regulation by allowing physical access to transcription factors. The advent of second-generation sequencing has enabled landmark genome-wide studies of nucleosome...

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Bibliographic Details
Main Authors: Polishko, Anton, Ponts, Nadia, Le Roch, Karine G., Lonardi, Stefano
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Ismb 2012 Proceedings Papers Committee July 15 to July 19, 2012, Long Beach, Ca, Usa
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371838/
https://ncbi.nlm.nih.gov/pubmed/22689767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts206
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