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NOrMAL: accurate nucleosome positioning using a modified Gaussian mixture model
Motivation: Nucleosomes are the basic elements of chromatin structure. They control the packaging of DNA and play a critical role in gene regulation by allowing physical access to transcription factors. The advent of second-generation sequencing has enabled landmark genome-wide studies of nucleosome...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371838/ https://ncbi.nlm.nih.gov/pubmed/22689767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts206 |
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