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Alcohol Inhibits Smooth Muscle Cell Proliferation via Regulation of the Notch Signaling Pathway

OBJECTIVE: To determine the role of Notch signaling in mediating alcohol’s inhibition of smooth muscle cell (SMC) proliferation. METHODS AND RESULTS: Treatment of human coronary artery SMCs with ethanol (EtOH) decreased Notch 1 mRNA and Notch 1 intracellular domain protein levels, in the absence of...

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Hlavní autoři: Morrow, David, Cullen, John P., Liu, Weimin, Cahill, Paul A., Redmond, Eileen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371770/
https://ncbi.nlm.nih.gov/pubmed/20930168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.215681
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