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Ethanol inhibits γ-secretase proteolytic activity in vascular smooth muscle cells
BACKGROUND: Ethanol (EtOH) inhibits Notch-mediated vascular smooth muscle cell (SMC) proliferation, an event that is key in vessel remodeling and atherogenesis. The object of this study was to determine if EtOH inhibits Notch signaling in SMC at the level of γ-secretase, a protease that in concert w...
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| Publicado no: | Alcohol Clin Exp Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624494/ https://ncbi.nlm.nih.gov/pubmed/26443551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12875 |
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