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Perivascular Delivery of Notch 1 siRNA Inhibits Injury-Induced Arterial Remodeling

OBJECTIVES: To determine the efficacy of perivascular delivery of Notch 1 siRNA in preventing injury-induced arterial remodeling. METHODS AND RESULTS: Carotid artery ligation was performed to induce arterial remodeling. After 14 days, morphometric analysis confirmed increased vSMC growth and subsequ...

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Detalhes bibliográficos
Main Authors: Redmond, Eileen M., Liu, Weimin, Hamm, Katie, Hatch, Ekaterina, Cahill, Paul A., Morrow, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885538/
https://ncbi.nlm.nih.gov/pubmed/24416200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084122
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