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Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survival

The role of glycogen synthase kinase 3 beta (GSK-3β) in modulating Notch control of vascular smooth muscle cell (vSMC) growth (proliferation and apoptosis) was examined in vitro under varying conditions of cyclic strain and validated in vivo following changes in medial tension and stress. Modulation...

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Detalhes bibliográficos
Main Authors: Guha, Shaunta, Cullen, John P., Morrow, David, Colombo, Alberto, Lally, Caitríona, Walls, Dermot, Redmond, Eileen M., Cahill, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377369/
https://ncbi.nlm.nih.gov/pubmed/21557011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-011-0189-5
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