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A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?
Chromosomal common fragile sites (CFSs) are unstable genomic regions that break under replication stress and are involved in structural variation. They frequently are sites of chromosomal rearrangements in cancer and of viral integration. However, CFSs are undercharacterized at the molecular level a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371707/ https://ncbi.nlm.nih.gov/pubmed/22456607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.134395.111 |
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