Accurate typing of short tandem repeats from genome-wide sequencing data and its applications

Short tandem repeats (STRs) are implicated in dozens of human genetic diseases and contribute significantly to genome variation and instability. Yet profiling STRs from short-read sequencing data is challenging because of their high sequencing error rates. Here, we developed STR-FM, short tandem rep...

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Veröffentlicht in:Genome Res
Hauptverfasser: Fungtammasan, Arkarachai, Ananda, Guruprasad, Hile, Suzanne E., Su, Marcia Shu-Wei, Sun, Chen, Harris, Robert, Medvedev, Paul, Eckert, Kristin, Makova, Kateryna D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417121/
https://ncbi.nlm.nih.gov/pubmed/25823460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.185892.114
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