Accurate typing of short tandem repeats from genome-wide sequencing data and its applications

Short tandem repeats (STRs) are implicated in dozens of human genetic diseases and contribute significantly to genome variation and instability. Yet profiling STRs from short-read sequencing data is challenging because of their high sequencing error rates. Here, we developed STR-FM, short tandem rep...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Fungtammasan, Arkarachai, Ananda, Guruprasad, Hile, Suzanne E., Su, Marcia Shu-Wei, Sun, Chen, Harris, Robert, Medvedev, Paul, Eckert, Kristin, Makova, Kateryna D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417121/
https://ncbi.nlm.nih.gov/pubmed/25823460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.185892.114
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