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Alterations of Endocannabinoid Signaling, Synaptic Plasticity, Learning, and Memory in Monoacylglycerol Lipase Knock-out Mice

Endocannabinoid (eCB) signaling is tightly regulated by eCB biosynthetic and degradative enzymes. The eCB 2-arachidonoylglycerol (2-AG) is hydrolyzed primarily by monoacylglycerol lipase (MAGL). Here, we investigated whether eCB signaling, synaptic function, and learning behavior were altered in MAG...

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Detalhes bibliográficos
Main Authors: Pan, Bin, Wang, Wei, Zhong, Peng, Blankman, Jacqueline L., Cravatt, Benjamin F., Liu, Qing-song
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371386/
https://ncbi.nlm.nih.gov/pubmed/21940435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2075-11.2011
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