Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum123

Endocannabinoids are diffusible lipophilic molecules that may spread to neighboring synapses. Monoacylglycerol lipase (MAGL) is the principal enzyme that degrades the endocannabinoid 2-arachidonoylglycerol (2-AG). Using knock-out mice in which MAGL is deleted globally or selectively in neurons and a...

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Detalles Bibliográficos
Publicado en:eNeuro
Main Authors: Chen, Yao, Liu, Xiaojie, Vickstrom, Casey R., Liu, Michelle J., Zhao, Li, Viader, Andreu, Cravatt, Benjamin F., Liu, Qing-song
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2016
Assuntos:
New Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865651/
https://ncbi.nlm.nih.gov/pubmed/27182552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0048-16.2016
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