Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum123

Endocannabinoids are diffusible lipophilic molecules that may spread to neighboring synapses. Monoacylglycerol lipase (MAGL) is the principal enzyme that degrades the endocannabinoid 2-arachidonoylglycerol (2-AG). Using knock-out mice in which MAGL is deleted globally or selectively in neurons and a...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Chen, Yao, Liu, Xiaojie, Vickstrom, Casey R., Liu, Michelle J., Zhao, Li, Viader, Andreu, Cravatt, Benjamin F., Liu, Qing-song
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865651/
https://ncbi.nlm.nih.gov/pubmed/27182552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0048-16.2016
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