APOBEC3G Expression and Hypermutation Are Inversely Associated With Human Immunodeficiency Virus Type 1 (HIV-1) Burden In Vivo

APOBEC3G (A3G) and APOBEC3F (A3F) reduce Vif-negative HIV-1 provirus formation and cause disabling provirus G-to-A hypermutation in vitro. However, evidence conflicts about whether they negatively impact Vif-positive HIV-1, or only enhance virus genetic diversity, in vivo. We studied peripheral bloo...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Kourteva, Yordanka, De Pasquale, MariaPia, Allos, Tara, McMunn, Chara, D’Aquila, Richard T.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371094/
https://ncbi.nlm.nih.gov/pubmed/22579353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.03.018
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items