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APOBEC3G Expression and Hypermutation Are Inversely Associated With Human Immunodeficiency Virus Type 1 (HIV-1) Burden In Vivo
APOBEC3G (A3G) and APOBEC3F (A3F) reduce Vif-negative HIV-1 provirus formation and cause disabling provirus G-to-A hypermutation in vitro. However, evidence conflicts about whether they negatively impact Vif-positive HIV-1, or only enhance virus genetic diversity, in vivo. We studied peripheral bloo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371094/ https://ncbi.nlm.nih.gov/pubmed/22579353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.03.018 |
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