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Role of APOBEC3G/F-Mediated Hypermutation in the Control of Human Immunodeficiency Virus Type 1 in Elite Suppressors

While many studies show that the APOBEC3 family of cytidine deaminases can inhibit human immunodeficiency virus type 1 (HIV-1) replication, the clinical significance of this host defense mechanism is unclear. Elite suppressors are HIV-1-infected individuals who maintain viral loads below 50 copies/m...

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Detalhes bibliográficos
Main Authors: Gandhi, Shiv K., Siliciano, Janet D., Bailey, Justin R., Siliciano, Robert F., Blankson, Joel N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259015/
https://ncbi.nlm.nih.gov/pubmed/18077705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01533-07
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