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Distinct Domains within APOBEC3G and APOBEC3F Interact with Separate Regions of Human Immunodeficiency Virus Type 1 Vif

Human APOBEC3G (A3G) and APOBEC3F (A3F) inhibit the replication of Vif-deficient human immunodeficiency virus type 1 (HIV-1). HIV-1 Vif overcomes these host restriction factors by binding to them and inducing their degradation. Thus, the Vif-A3G and Vif-A3F interactions are attractive targets for an...

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Autori principali: Russell, Rebecca A., Smith, Jessica, Barr, Rebekah, Bhattacharyya, Darshana, Pathak, Vinay K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643761/
https://ncbi.nlm.nih.gov/pubmed/19036809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01621-08
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