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Gentamicin Rapidly Inhibits Mitochondrial Metabolism in High-Frequency Cochlear Outer Hair Cells

Aminoglycosides (AG), including gentamicin (GM), are the most frequently used antibiotics in the world and are proposed to cause irreversible cochlear damage and hearing loss (HL) in 1/4 of the patients receiving these life-saving drugs. Akin to the results of AG ototoxicity studies, high-frequency,...

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מידע ביבליוגרפי
Main Authors: Jensen-Smith, Heather C., Hallworth, Richard, Nichols, Michael G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371036/
https://ncbi.nlm.nih.gov/pubmed/22715386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038471
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