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The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress-induced transcription factor KLF2 on regulation a...

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Hlavní autoři: van Agtmaal, Ellen L., Bierings, Ruben, Dragt, Bieuwke S., Leyen, Thomas A., Fernandez-Borja, Mar, Horrevoets, Anton J. G., Voorberg, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371018/
https://ncbi.nlm.nih.gov/pubmed/22715381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038399
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