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The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress-induced transcription factor KLF2 on regulation a...

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Detalhes bibliográficos
Main Authors: van Agtmaal, Ellen L., Bierings, Ruben, Dragt, Bieuwke S., Leyen, Thomas A., Fernandez-Borja, Mar, Horrevoets, Anton J. G., Voorberg, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371018/
https://ncbi.nlm.nih.gov/pubmed/22715381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038399
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