The Shear Stress-Induced Transcription Factor KLF2 Affects Dynamics and Angiopoietin-2 Content of Weibel-Palade Bodies

BACKGROUND: The shear-stress induced transcription factor KLF2 has been shown to induce an atheroprotective phenotype in endothelial cells (EC) that are exposed to prolonged laminar shear. In this study we characterized the effect of the shear stress-induced transcription factor KLF2 on regulation a...

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Главные авторы: van Agtmaal, Ellen L., Bierings, Ruben, Dragt, Bieuwke S., Leyen, Thomas A., Fernandez-Borja, Mar, Horrevoets, Anton J. G., Voorberg, Jan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371018/
https://ncbi.nlm.nih.gov/pubmed/22715381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038399
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