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Phosphorylation of p65(RelA) on Ser(547) by ATM Represses NF-κB-Dependent Transcription of Specific Genes after Genotoxic Stress
The NF-κB pathway is involved in immune and inflammation responses, proliferation, differentiation and cell death or survival. It is activated by many external stimuli including genotoxic stress. DNA double-strand breaks activate NF-κB in an ATM-dependent manner. In this manuscript, a direct interac...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371017/ https://ncbi.nlm.nih.gov/pubmed/22715377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038246 |
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