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Crystallization and preliminary X-ray analysis of the C-terminal domain of CCM2, part of a novel adaptor protein involved in cerebral cavernous malformations

Cerebral cavernous malformation 2 (CCM2) is a novel two-domain adaptor protein which participates in multiple cellular signalling pathways. Loss-of-function mutations in the gene encoding CCM2 are the cause of common human vascular lesions called cerebral cavernous malformations. Here, the purificat...

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Bibliografske podrobnosti
Main Authors: Wang, Xiaoyan, Ding, Jingjin, Wang, Dacheng
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370910/
https://ncbi.nlm.nih.gov/pubmed/22684070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112016181
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