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Deletions in CCM2 Are a Common Cause of Cerebral Cavernous Malformations

Cerebral cavernous malformations (CCMs) are vascular abnormalities of the brain that can result in a variety of neurological disabilities, including hemorrhagic stroke and seizures. Mutations in the gene KRIT1 are responsible for CCM1, mutations in the gene MGC4607 are responsible for CCM2, and muta...

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Detalhes bibliográficos
Main Authors: Liquori, Christina L., Berg, Michel J., Squitieri, Ferdinando, Leedom, Tracey P., Ptacek, Louis, Johnson, Eric W., Marchuk, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785317/
https://ncbi.nlm.nih.gov/pubmed/17160895
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