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Crystallization and preliminary crystallographic studies of CCM3 in complex with the C-terminal domain of MST4

MST4 is a member of the GCKIII kinases. The interaction between cerebral cavernous malformation 3 (CCM3) and GCKIII kinases plays a critical role in cardiovascular development and in cerebral cavernous malformations. The complex of CCM3 and the C-terminal domain of MST4 has been constructed, purifie...

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Detalhes bibliográficos
Main Authors: Xu, Xueyong, Wang, Xiaoyan, Ding, Jingjin, Wang, Da-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388915/
https://ncbi.nlm.nih.gov/pubmed/22750858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112016843
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