Efficacy of Combined Therapy with Liposome-Encapsulated Meglumine Antimoniate and Allopurinol in Treatment of Canine Visceral Leishmaniasis

An innovative liposomal formulation of meglumine antimoniate (LMA) was recently reported to promote both long-term parasite suppression and reduction of infectivity to sand flies in dogs with visceral leishmaniasis. However, 5 months after treatment, parasites were still found in the bone marrow of...

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Autori principali: da Silva, Sydnei M., Amorim, Izabela F. G., Ribeiro, Raul R., Azevedo, Erly G., Demicheli, Cynthia, Melo, Maria N., Tafuri, Wagner L., Gontijo, Nelder F., Michalick, Marilene S. M., Frézard, Frédéric
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370762/
https://ncbi.nlm.nih.gov/pubmed/22411610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00208-12
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