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Glutathione-Induced Conversion of Pentavalent Antimony to Trivalent Antimony in Meglumine Antimoniate

The standard treatment of human leishmaniases involves the use of pentavalent antimony [Sb(V)] compounds, including meglumine antimoniate. The mode of action of these compounds has not been fully elucidated. The possibility that Sb(III) is involved has been suggested; however, the biomolecule that m...

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Detalhes bibliográficos
Main Authors: Frézard, Frédéric, Demicheli, Cynthia, Ferreira, Claúdio S., Costa, Michelle A. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90392/
https://ncbi.nlm.nih.gov/pubmed/11181379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.913-916.2001
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