Reduced Tissue Parasitic Load and Infectivity to Sand Flies in Dogs Naturally Infected by Leishmania (Leishmania) chagasi following Treatment with a Liposome Formulation of Meglumine Antimoniate

The toxicity and antileishmanial effectiveness of a novel liposome formulation of meglumine antimoniate in mongrel dogs with visceral leishmaniasis (VL) obtained from a region where VL is endemic in Brazil have been investigated. Groups of 12 animals received by the intravenous route four doses (wit...

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Hauptverfasser: Ribeiro, Raul R., Moura, Eliane P., Pimentel, Vitor M., Sampaio, Weverton M., Silva, Sydnei M., Schettini, Dante A., Alves, Cintia F., Melo, Ferdinan A., Tafuri, Wagner L., Demicheli, Cynthia, Melo, Maria N., Frézard, Frédéric, Michalick, Marilene S. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443916/
https://ncbi.nlm.nih.gov/pubmed/18458133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00223-08
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