Biodistribution of meglumine antimoniate in healthy and Leishmania (Leishmania) infantum chagasi-infected BALB/c mice

Pentavalent antimonials such as meglumine antimoniate (MA) are the primary treatments for leishmaniasis, a complex disease caused by protozoan parasites of the genus Leishmania . Despite over 70 years of clinical use, their mechanisms of action, toxicity and pharmacokinetics have not been fully eluc...

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Autores principales: Borborema, Samanta Etel Treiger, Osso, João Alberto, de Andrade, Heitor Franco, do Nascimento, Nanci
Formato: Artigo
Lenguaje:Inglês
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970594/
https://ncbi.nlm.nih.gov/pubmed/23903979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-0276108052013014
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