Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice

Pentavalent antimonial has been the first choice treatment for visceral leishmaniasis; however, it has several side effects that leads to low adherence to treatment. Liposome-encapsulated meglumine antimoniate (MA) arises as an important strategy for chemotherapy enhancement. We evaluated the immuno...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Reis, Levi Eduardo Soares, Fortes de Brito, Rory Cristiane, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, Aguiar Soares, Rodrigo Dian Oliveira, Carneiro, Claudia Martins, de Abreu Vieira, Paula Melo, Ramos, Guilherme Santos, Frézard, Frédéric Jean Georges, Roatt, Bruno Mendes, Reis, Alexandre Barbosa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655062/
https://ncbi.nlm.nih.gov/pubmed/28827416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00962-17
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