Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice

Pentavalent antimonial has been the first choice treatment for visceral leishmaniasis; however, it has several side effects that leads to low adherence to treatment. Liposome-encapsulated meglumine antimoniate (MA) arises as an important strategy for chemotherapy enhancement. We evaluated the immuno...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Reis, Levi Eduardo Soares, Fortes de Brito, Rory Cristiane, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, Aguiar Soares, Rodrigo Dian Oliveira, Carneiro, Claudia Martins, de Abreu Vieira, Paula Melo, Ramos, Guilherme Santos, Frézard, Frédéric Jean Georges, Roatt, Bruno Mendes, Reis, Alexandre Barbosa
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655062/
https://ncbi.nlm.nih.gov/pubmed/28827416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00962-17
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