Efficacy of Meglumine Antimoniate in a Low Polymerization State Orally Administered in a Murine Model of Visceral Leishmaniasis

Progress toward the improvement of meglumine antimoniate (MA), commercially known as Glucantime, a highly effective but also toxic antileishmanial drug, has been hindered by the lack of knowledge and control of its chemical composition. Here, MA was manipulated chemically with the aim of achieving a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Kato, Kelly C., de Morais-Teixeira, Eliane, Islam, Arshad, Leite, M. Fatima, Demicheli, Cynthia, de Castro, Whocely V., Corrêa-Junior, José D., Rabello, Ana, Frézard, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2018
Pynciau:
Experimental Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105864/
https://ncbi.nlm.nih.gov/pubmed/29866873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00539-18
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