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Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma
To gain more insight into the role of chromosomal instability (CIN), the cytogenetic hallmark of most solid tumors, we performed fluorescence in situ hybridization (FISH) on interphase nuclei of cytological specimens enabling the correct detection of chromosome copies in intact tumor cells of 18 wel...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC337049/ https://ncbi.nlm.nih.gov/pubmed/14745031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305817101 |
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