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Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
The mitotic checkpoint guards against chromosome missegregation and the production of aneuploid daughter cells. Aneuploidy is a common characteristic of tumor cells and has been proposed for over a century to drive tumor progression. However, recent evidence has revealed that although aneuploidy can...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154738/ https://ncbi.nlm.nih.gov/pubmed/19546858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2718 |
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