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Losing balance: the origin and impact of aneuploidy in cancer
Most solid human tumours are aneuploid, that is, they contain an abnormal number of chromosomes. Paradoxically, however, aneuploidy has been reported to induce a stress response that suppresses cellular proliferation in vitro. Here, we review the progress in our understanding of the causes and effec...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367240/ https://ncbi.nlm.nih.gov/pubmed/22565320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.55 |
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