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Caspase cleavage of Bim(EL) triggers a positive feedback amplification of apoptotic signaling
Members of the Bcl-2 protein family that share only the Bcl-2 homology 3 (BH3) domain are known mostly as sentinels for apoptotic stimuli and initiators of apoptosis. One BH3-only protein, Bim, is the major physiological antagonist of the prosurvival proteins in B and T lymphocytes. It is required f...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC337036/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14732682/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308050100 |
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