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Caspase cleavage of Bim(EL) triggers a positive feedback amplification of apoptotic signaling

Members of the Bcl-2 protein family that share only the Bcl-2 homology 3 (BH3) domain are known mostly as sentinels for apoptotic stimuli and initiators of apoptosis. One BH3-only protein, Bim, is the major physiological antagonist of the prosurvival proteins in B and T lymphocytes. It is required f...

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Bibliografische gegevens
Hoofdauteurs: Chen, Dan, Zhou, Qiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC337036/
https://ncbi.nlm.nih.gov/pubmed/14732682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308050100
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