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Family-Based Association Studies for Next-Generation Sequencing

An individual's disease risk is determined by the compounded action of both common variants, inherited from remote ancestors, that segregated within the population and rare variants, inherited from recent ancestors, that segregated mainly within pedigrees. Next-generation sequencing (NGS) techn...

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Bibliographic Details
Main Authors: Zhu, Yun, Xiong, Momiao
Format: Artigo
Language:Inglês
Published: Elsevier 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370281/
https://ncbi.nlm.nih.gov/pubmed/22682329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.04.022
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