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Implication of next-generation sequencing on association studies

BACKGROUND: Next-generation sequencing technologies can effectively detect the entire spectrum of genomic variation and provide a powerful tool for systematic exploration of the universe of common, low frequency and rare variants in the entire genome. However, the current paradigm for genome-wide as...

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Bibliographic Details
Main Authors: Siu, Hoicheong, Zhu, Yun, Jin, Li, Xiong, Momiao
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148210/
https://ncbi.nlm.nih.gov/pubmed/21682891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-322
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