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Pathway analysis with next-generation sequencing data
Although pathway analysis methods have been developed and successfully applied to association studies of common variants, the statistical methods for pathway-based association analysis of rare variants have not been well developed. Many investigators observed highly inflated false-positive rates and...
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Publicado no: | Eur J Hum Genet |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4666565/ https://ncbi.nlm.nih.gov/pubmed/24986826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.121 |
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