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Pathway analysis with next-generation sequencing data

Although pathway analysis methods have been developed and successfully applied to association studies of common variants, the statistical methods for pathway-based association analysis of rare variants have not been well developed. Many investigators observed highly inflated false-positive rates and...

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Détails bibliographiques
Publié dans:Eur J Hum Genet
Auteurs principaux: Zhao, Jinying, Zhu, Yun, Boerwinkle, Eric, Xiong, Momiao
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666565/
https://ncbi.nlm.nih.gov/pubmed/24986826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.121
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